网页Using a custom fabricated cellulose acetate membrane, Ryu et al. created a further type of coculture system where cells on either side of the membrane were in much closer contact through the membrane pores. 74 The porosity of the membrane was shown to be greater than 50%, while the membrane thickness was less than 500 nm for all the pore
网页The bubble point test is the de facto standard for postproduction filter membrane integrity test in the radiopharmaceutical community. However, the bubble point test depends on a subjective visual assessment of bubbling rate that can be obscured by significant diffusive gas flows below the manufactu
网页2021年5月28日 · The basic condition for the tests is complete wetting of the filter membrane pores utilizing a wetting fluid such as water, buffer or the product for filtration. For hydrophobic membranes that will not wet with water, a low surface tension liquid such as a mixture of alcohol and water, is required. An alternative test method, that can be used
网页At pressures below the bubble point, gas passes across the filter only by diffusion, but when the pressure is high enough to dislodge liquid from the pores, bulk flow begins and
网页2019年12月13日 · The bubble point test is significant not only for indicating maximum pore size, but may also indicate a damaged membrane, ineffective seals, or a system leak. 5.3 The results of this test method should not be used as the sole factor to describe the limiting size for retention of particulate contaminants from fluids.
网页For membrane or filter areas of 2.4 or 8 m 2, bubble point and largest pore diameter can be readily measured. The maximum pore diameter d max can be calculated from the pressure in the gas compartment P B corresponding to the bubble point by means of
网页2008年12月1日 · Issue Section: Letters. In a recent article on caspofungin acetate compatibility, the bubble-point test of filter membranes—used to collect
网页2022年8月19日 · A Bubble Point of a membrane filter is the pressure at which air will pass through the filter when it is wetted. This pressure is related to the pore size of the membrane and so this pressure measurement can be used to determine both the pore
网页A bubble point test is a non-destructive method of integrity testing that allows the user to correlate their results with manufacturer-determined values that indicate proper function.
网页Bubble Point. Bubble point is a function of pore size, filter medium wettability, surface tension and angle of contact. The filter membrane is wetted and a gradual increasing
网页2017年7月17日 · The bubble point of the test filter is reached when bubbles are produced from the tube at a steady rate. Purpose This test is completed to estimate the pore size of microporous filters and to confirm the integrity of sterilizing membrane filters
网页Der Bubble-Point-Test (auch: Blasendruck-Test oder Blaspunkt-Messung) wird zur Qualitätsprüfung von Membranen verwendet. Er ist speziell bei der Sterilfiltration von Bedeutung. Der Blaspunkt ist neben dem Berstdruck und dem Wasserwert eine der einfachsten und zuverlässigsten Möglichkeiten, die Eigenschaften eines Filter elementes